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Mcnerney, Megan
One or more keywords matched the following items that are connected to
Mcnerney, Megan
Item Type
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Concept
Nuclear Proteins
Academic Article
Regulatory defects in Cbl and mitogen-activated protein kinase (extracellular signal-related kinase) pathways cause persistent hyperexpression of CD40 ligand in human lupus T cells.
Academic Article
CUX1 is a haploinsufficient tumor suppressor gene on chromosome 7 frequently inactivated in acute myeloid leukemia.
Academic Article
The spectrum of somatic mutations in high-risk acute myeloid leukaemia with -7/del(7q).
Academic Article
The haploinsufficient tumor suppressor, CUX1, acts as an analog transcriptional regulator that controls target genes through distal enhancers that loop to target promoters.
Academic Article
Gene dosage effect of CUX1 in a murine model disrupts HSC homeostasis and controls the severity and mortality of MDS.
Academic Article
Loss of a 7q gene, CUX1, disrupts epigenetically driven DNA repair and drives therapy-related myeloid neoplasms.
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Nuclear Proteins